We discuss socio-demographic data of the diet-retreat users at Centro Takiwasi from 2012-2017, describing as well the main plants used for this medical practice inspired by the local Amazonian traditional knowledge. In the past two decades, the dieta has become increasingly popular among a global audience as an alternative form of healing for various physical and mental health conditions.
Central to Amazonian shamanism in Peru is the dieta (diet-retreat), a practice of drinking plant preparations in isolation in the rainforest while observing dietary restrictions, abstaining from social relations, sexual activities, and the use of perfumes. This article presents data related to diet-retreat users at Centro Takiwasi, a therapeutic community that specializes in addiction rehabilitation based on a protocol that combines western psychotherapy with traditional Amazonian medicine. Conclusion: It was demonstrated the antidepressant-like activity of the ethanolic extract of the leaves of Maytenus macrocarpa with a dose of 500 mg/kg and an antipsychotic-like activity with a dose of 1000 mg/kg. It was seen a positive dose-response between the dose of 500 to 1000 mg/Kg (Pearson correlation of r=0.8339 and R=0.6954) and a negative dose-response between the dose of 1000 to 1500 mg/Kg. Results: The immobility time of the groups of EELMM has a mean of 38.26 ± 21.57, 84.32 ± 26.68 and 32.17 ± 25.55 for the doses of 750, 10 mg/Kg respectively and the immobility time had a median of 7.5 and 20.93 ± for the doses of 500 mg/Kg and 1500 mg/Kg. As control, it was used distillate water, fluoxetine and haloperidol.
Methods: It was used the ethanolic extract of the leaves of Maytenus macrocarpa (EELMM) in female mice at the experimental model of the Forced Swim Test described by Porsolt. For this reason, the aim of this study was to determinate the antidepressant and antipsychotic-like activity of the ethanolic extract of Maytenus macrocarpa. In addition, depression is a disorder of the mood that cause disability to millions of people around the world. Also, chuchuhuasi is known as a master plant, attributing to it properties in the central nervous system. Introduction: Maytenus macrocarpa (Chuchuhuasi) is an Amazonian Peruvian traditional plant, traditionally used as anti-inflammatory, antipyretic, antihemorrhagic and antidiarrheic agent.
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